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Article

Development of a humanized HLA‐A30 transgenic mouse model

6 Jul 2022

Abstract excerpt

BACKGROUND: There are remarkable genetic differences between animal major histocompatibility complex (MHC) systems and the human leukocyte antigen (HLA) system. HLA transgenic humanized mouse model systems offer a much better method to study the HLA-A-related principal mechanisms for vaccine development and HLA-A-restricted responses against infection in human. METHODS: , linked at its N-terminus to the...

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PMID: 35791899
DOI: 10.1002/ame2.12225

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