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Article

Hemagglutinating Virus of Japan (HVJ) Envelope Vector as a Versatile Gene Delivery System

1 Aug 2002

Abstract excerpt

We have developed a simple method for converting the lipid envelope of an inactivated virus to a gene transfer vector. Hemagglutinating virus of Japan (HVJ; Sendai virus) envelope vector was constructed by incorporating plasmid DNA into inactivated HVJ particles. This HVJ envelope vector introduced plasmid DNA efficiently and rapidly into various cell lines, including cancer cells and several types of primary...

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Identifiers

PMID: 12161188
DOI: 10.1006/mthe.2002.0647

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