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Article

A pulsed current electric field alters protein expression creating a wound healing phenotype in human skin cells.

Regenerative medicine - 1 May 2020

Bostan Luciana E, Almqvist Sofia, Pullar Christine E

Abstract excerpt

Aim: Pulsed current (PC) electric field (EF) devices promote healing in chronic wounds but the underpinning mechanisms are largely unknown. The gap between clinical evidence and mechanistic understanding limits device uptake in clinics. Materials & methods: Migration, proliferation and gene/protein expression profiles were investigated in the presence/absence of PCEF, in skin: keratinocytes (NHK); dermal...

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Identifiers

PMID: 32633622
DOI: 10.2217/rme-2019-0087

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