Article
A polymorphism of the interleukin-6 gene promoter and idiopathic recurrent miscarriage.
Human reproduction (Oxford, England) - 1 Feb 2003
Unfried G, Böcskör S, Endler G, Nagele F, Huber J C, Tempfer C B
Abstract excerpt
BACKGROUND: Cytokines have been described to play a major role in the pathogenesis of idiopathic recurrent miscarriage (IRM). We investigated the association between IRM and a polymorphism of the interleukin-6 (IL-6) gene and IL-6 serum levels. METHODS: In a prospective case-control study, we studied 161 women with IRM and 124 healthy controls. Peripheral venous puncture, DNA extraction and PCR were employed to...
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