Article
A polymorphism of the interleukin-1beta gene and idiopathic recurrent miscarriage.
Fertility and sterility - 1 Aug 2001
Hefler L A, Tempfer C B, Unfried G, Schneeberger C, Lessl K, Nagele F, Huber J C
Abstract excerpt
OBJECTIVE: Proinflammatory cytokines have been described to be involved in the pathogenesis of idiopathic recurrent miscarriage (IRM). We investigated the association between IRM and a polymorphism in exon 5 of the interleukin-1beta gene (IL1B) and interleukin-1beta (IL-1beta) serum levels. DESIGN: Case control study. SETTING: Academic research institution. SUBJECTS: One hundred thirty-one women with a history of...
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