Article
Association between TNF, IL1B, IL6, IL10 and IFNG polymorphisms and recurrent miscarriage: a case control study.
Reproductive biology and endocrinology : RB&E - 10 Oct 2017
Ma Jianting, Zhang Xingguang, He Gang, Yang Chunlin
Abstract excerpt
BACKGROUND: Approximately half of recurrent miscarriages have unexplained etiology. Recent evidences suggest that cytokines are important determinants in pregnancy maintenance and as such, cytokine gene polymorphisms, which can affect cytokine production and/or functionality, could play a role in the disorder. Thus, we aimed to investigate the association of selected cytokine gene polymorphisms with risk of...
Topics
- Abortion, Habitual
- Adult
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interferon-gamma
- Interleukin-10
- Interleukin-1beta
- Interleukin-6
- Polymorphism, Single Nucleotide
- Pregnancy
- Tumor Necrosis Factor-alpha
- Young Adult