Article
Environment-gene interactions in intestinal cancer.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Aug 2002
Augenlicht Leonard H, Heerdt Barbara G, Mariadason John M, Yang WanCai, Wilson Andrew J, Fragale Alessandra, Velcich Anna
Abstract excerpt
Only 5-10% of all colorectal cancer in the United States can be directly attributed to inheritance of genetic predisposition for tumor development. Thus, the vast majority of colorectal cancer is classified as sporadic, and in these patients environmental factors--particularly the diet--play a major role in determining the probability of tumor formation and its progression. Investigations of how dietary...
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