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Article

Genetic and environmental factors in colorectal carcinogenesis.

Digestive diseases (Basel, Switzerland) - 1 Jan 2000

Zimbalist E H, Plumer A R

Abstract excerpt

The molecular genetic mechanisms of colorectal cancer are among the best understood of any common cancer. Recent research has identified mutated tumor suppressor genes and oncogenes as normal tissue progresses from benign to malignant, and the novel mismatch repair genes involved in a specific form of hereditary colorectal cancer as well as a significant percentage of sporadic cases. This information has led to a...

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PMID: 8590523
DOI: 10.1159/000171516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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