Article
Allelic variation in the serotonin transporter promoter affects neuromodulatory effects of a selective serotonin transporter reuptake inhibitor (SSRI).
Psychopharmacology - 1 Mar 2003
Eichhammer Peter, Langguth Berthold, Wiegand Rainer, Kharraz Alexander, Frick Ulrich, Hajak Göran
Abstract excerpt
RATIONALE: Antidepressant efficacy of selective serotonin reuptake inhibitors (SSRIs) has been shown to depend on functional polymorphisms within the promoter region of the serotonin transporter gene (5-HTTLPR). This gene gives rise to a biallelic polymorphism designated long (l) and short (s). H...
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