Article
Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development.
Pharmacogenetics - 1 Feb 2003
Choi Ji-Yeob, Abel Josef, Neuhaus Thomas, Ko Yon, Harth Volker, Hamajima Nobuyuki, Tajima Kazuo, Yoo Keun-Young, Park Sue Kyung, Noh Dong-Young, Han Wonshik, Choe Kuk-Jin, Ahn Sei-Hyun, Kim Sook-Un, Hirvonen Ari, Kang Daehee
Abstract excerpt
OBJECTIVE: We examined the potential association between alcohol consumption and genetic polymorphisms in the alcohol metabolizing enzymes, CYP2E1 and ALDH2, in individual susceptibility to breast cancer in a Korean study population. METHODS: Three hundred and forty-six histologically confirmed breast cancer patients and 377 controls with no present or previous history of cancer were recruited from several...
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