Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women.

doi:10.1038/s41598-020-62361-9

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Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women.

Scientific reports - 16 Apr 2020

Park Boyoung, Kim Ji-Hyun, Lee Eun Sook, Jung So-Youn, Lee See Youn, Kang Han-Sung, Lee Eun-Gyeong, Han Jai Hong

Abstract excerpt

The associations between genetic polymorphisms in ADH1B (rs1229984) and ALDH2 (rs671), alcohol consumption, the effect of a combination of the two polymorphisms, and breast cancer risk were studied in a population of East-Asian women. In this study, 623 breast cancer cases and 1845 controls, aged 40 or above, were included. The association between ALDH2 polymorphism and breast cancer risk was validated in 2143...

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Alcohol Dehydrogenase
Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aldehyde Dehydrogenase, Mitochondrial

Asian People

Breast Neoplasms

Menopause

Polymorphism, Single Nucleotide

Risk Factors

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Identifiers

PMID: 32300124
DOI: 10.1038/s41598-020-62361-9
PMCID: PMC7162854

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