Article
Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels.
Plastic and reconstructive surgery - 1 Feb 2003
Bayat Ardeshir, Bock Oliver, Mrowietz Uli, Ollier William E R, Ferguson Mark W J
Abstract excerpt
Keloid disease and hypertrophic scars are dermal tumors that are often familial and typically occur in certain races. Their exact etiology is still unknown. Transforming growth factor beta1 (TGF-beta1) plays a central role in wound healing and fibrosis and has been implicated in the pathogenesis of keloid disease and hypertrophic scar. The aims of this study were to measure the plasma level of TGF-beta1 in...
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