Article
Association of TGFβ1 and SMAD4 variants in the etiology of keloid scar in the Malay population.
Archives of dermatological research - 1 Sept 2012
Emami Azadeh, Halim Ahmad Sukari, Salahshourifar Iman, Yussof Shah Jumaat Mohd, Khoo Teng Lye, Kannan Thirumulu Ponnuraj
Abstract excerpt
Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. In a case-control design, TGFβ1 haplotypes showed association with the risk of k...
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