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Article

Genetic susceptibility in Dupuytren's disease. TGF-beta1 polymorphisms and Dupuytren's disease.

The Journal of bone and joint surgery. British volume - 1 Mar 2002

Bayat A, Watson J S, Stanley J K, Alansari A, Shah M, Ferguson M W J, Ollier W E R

Abstract excerpt

Dupuytren's disease is a benign fibroproliferative disease of unknown aetiology. It is often familial and commonly affects Northern European Caucasian men, but genetic studies have yet to identify the relevant genes. Transforming growth factor beta one (TGF-beta1) is a multifunctional cytokine which plays a central role in wound healing and fibrosis. It stimulates the proliferation of fibroblasts and the...

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Source

Identifiers

PMID: 11924651
DOI: 10.1302/0301-620x.84b2.12083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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