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Article

Architecture of succinate dehydrogenase and reactive oxygen species generation.

Science (New York, N.Y.) - 31 Jan 2003

Yankovskaya Victoria, Horsefield Rob, Törnroth Susanna, Luna-Chavez César, Miyoshi Hideto, Léger Christophe, Byrne Bernadette, Cecchini Gary, Iwata So

Abstract excerpt

The structure of Escherichia coli succinate dehydrogenase (SQR), analogous to the mitochondrial respiratory complex II, has been determined, revealing the electron transport pathway from the electron donor, succinate, to the terminal electron acceptor, ubiquinone. It was found that the SQR redox centers are arranged in a manner that aids the prevention of reactive oxygen species (ROS) formation at the flavin...

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Identifiers

PMID: 12560550
DOI: 10.1126/science.1079605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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