Article
Detection of genetic abnormalities in neoplasms from Greek patients with FAP.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Feb 2003
Michalopoulos Nikolaos V, Saetta Angelica, Lazaris Andreas Ch, Voutsinas Gerassimos, Davaris Panayiotis S
Abstract excerpt
AIMS: DNA microsatellite instability is a well-known feature of hereditary non-polyposis colon cancer; however, its incidence in familial adenomatous polyposis, is unclear. We report the frequency of microsatellite instability and other genetic abnormalities in a group of Greek patients with FAP, in relation to various clinicopathological variables. METHODS: Thirty-four tissue specimens from 10 patients with FAP...
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