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Article

Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients.

BMC cancer - 22 Jul 2010

Fostira Florentia, Thodi Georgia, Sandaltzopoulos Raphael, Fountzilas George, Yannoukakos Drakoulis

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis, an autosomal dominant inherited disease caused by germline mutations within the APC gene, is characterized by early onset colorectal cancer as a consequence of the intrinsic phenotypic feature of multiple colorectal adenomatic polyps. The genetic investigation of Greek adenomatous polyposis families was performed in respects to APC and MUTYH germline mutations....

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Source

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Identifiers

PMID: 20649969
DOI: 10.1186/1471-2407-10-389
PMCID: PMC2918579

Genes

APC
FAP
MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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