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Article

Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients.

BMC cancer - 15 Apr 2005

Mihalatos Markos, Apessos Angela, Dauwerse Hans, Velissariou Voula, Psychias Aristidis, Koliopanos Alexander, Petropoulos Konstantinos, Triantafillidis John K, Danielidis Ioannis, Fountzilas George, Agnantis Niki J, Nasioulas Georgios

Abstract excerpt

BACKGROUND: Familial Adenomatous Polyposis (FAP) is caused by germline mutations in the APC (Adenomatous Polyposis Coli) gene. The vast majority of APC mutations are point mutations or small insertions/deletions which lead to truncated protein products. Splicing mutations or gross genomic rearrangements are less common inactivating events of the APC gene. METHODS: In the current study genomic DNA or RNA from ten...

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Identifiers

PMID: 15833136
DOI: 10.1186/1471-2407-5-40
PMCID: PMC1097718

Genes

APC
FAP

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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