Article
Polymorphisms for chemical metabolizing genes and risk for cervical neoplasia.
Environmental and molecular mutagenesis - 1 Jan 2003
Sierra-Torres Carlos H, Au William W, Arrastia Concepcion D, Cajas-Salazar Nohelia, Robazetti Sonia C, Payne Deborah A, Tyring Stephen K
Abstract excerpt
Infection with high-risk human papillomavirus (HPV) plays a major role in the etiology of cervical cancer (CC). However, most infected women do not develop cancer. Therefore, exposure to other carcinogenic agents may be a contributing risk factor for CC. We investigated the hypothesis that environmental exposure to cigarette smoke and inheritance of polymorphic chemical metabolizing genes (CYP2E1, GSTM1, and mEH)...
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