Relationship between GSTM1 and GSTT1 polymorphisms and HPV infection: a systematic review.

doi:10.1007/s11033-021-06515-6

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Article

Relationship between GSTM1 and GSTT1 polymorphisms and HPV infection: a systematic review.

Molecular biology reports - 1 Sept 2021

Bortolli Ana Paula Reolon, Vieira Valquíria Kulig, Stefanski Emi Elaine, Lazarotto Angela Khetly, Lucio Léia Carolina

Abstract excerpt

Human Papillomavirus (HPV) is the most important risk factor for cervical cancer, although not the only one. The allelic polymorphism of enzymes acting on carcinogen metabolism has shown to influence the risk of both intraepithelial lesions and cervical carcinogenesis. Several studies found an association between GSTM1/GSTT1 null genotypes and risk of cancer. This research aimed to review studies addressing the...

Topics

Alleles
Female
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Papillomaviridae
Papillomavirus Infections
Polymorphism, Single Nucleotide
Risk Factors
Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 34387803
DOI: 10.1007/s11033-021-06515-6

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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