Article
Rapid detection of exon 1 NRAS gene mutations using universal heteroduplex generator technology.
Human mutation - 1 Feb 2003
Belli Carolina, De Brasi Carlos, Larripa Irene
Abstract excerpt
Specific NRAS oncogene missense mutations have been frequently found in some tumors and several hematological diseases, especially in those of myeloid origin. There is a wide range of PCR-based methods for screening and detection of NRAS exon 1 single-base substitutions. However, there are disadvantages and ambiguities associated with these techniques because all of them require either separate probes, separate...
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