Article
The novel imprinted carboxypeptidase A4 gene ( CPA4) in the 7q32 imprinting domain.
Human genetics - 1 Mar 2003
Kayashima Tomohiko, Yamasaki Kentaro, Yamada Takahiro, Sakai Hideki, Miwa Nobutomo, Ohta Tohru, Yoshiura Koh-ichiro, Matsumoto Naomichi, Nakane Yoshibumi, Kanetake Hiroshi, Ishino Fumitoshi, Niikawa Norio, Kishino Tatsuya
Abstract excerpt
By a search for novel human imprinted genes in the vicinity of the imprinted gene MEST, at chromosome 7q32, we identified the carboxypeptidase A4 gene ( CPA4) in a gene cluster of the carboxypeptidase family, 200 kb centromeric to MEST. Because CPA4 was originally identified as a protein induced in a prostate cancer cell line (PC-3) by histone deacetylase inhibitors, and was located at the putative prostate...
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