Article
Development of a universal probe for electronic microarray and its application in characterization of the Staphylococcus aureus polC gene.
The Journal of molecular diagnostics : JMD - 1 Feb 2003
Cooper Kara L F, Goering Richard V
Abstract excerpt
Electronic microarray technology is an exceptionally accurate and effective technique for detecting and defining single nucleotide polymorphisms (SNPs) in DNA sequences. Target oligonucleotides are electronically addressed to a gel matrix containing streptavidin to which biotinylated polymerase chain reaction (PCR) amplicons are bound. Typically, a fluorescent-labeled reporter oligonucleotide specific for each...
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