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Enzymatic on-chip enhancement for high resolution genotyping DNA microarrays.

Analytical chemistry - 5 Jun 2012

Schulze Holger, Barl Timo, Vase Hollie, Baier Shiromi, Thomas Peter, Giraud Gerard, Crain Jason, Bachmann Till T

Abstract excerpt

Antibiotic resistance among pathogenic microorganisms is emerging as a major human healthcare concern. While there are a variety of resistance mechanisms, many can be related to single nucleotide polymorphisms and for which DNA microarrays have been widely deployed in bacterial genotyping. However, genotyping by means of allele-specific hybridization can suffer from the drawback that oligonucleotide probes with...

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PMID: 22548504
DOI: 10.1021/ac3007945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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