Article
Apoptosis caused by chemotherapeutic inhibition of nuclear factor-kappaB activation.
Cancer research - 15 Jan 2003
Biswas Debajit K, Martin Katherine J, McAlister Cliona, Cruz Antonio P, Graner Edgard, Dai Sun-chun, Pardee Arthur B
Abstract excerpt
Both the protein kinase C (alpha/beta) inhibitor Go6976 and expression of dominant-negative nuclear factor (NF)-kappaB inhibitor kinase mutants: (a) blocked the growth and caused regression of a mammary tumor insyngeneic mice; (b) inhibited epidermal growth factor (EGF)-induced activation, nuclea...
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