Article
Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595.
Journal of endotoxin research - 1 Jan 2002
Janusch Holger, Brecker Lothar, Lindner Buko, Alexander Christian, Gronow Sabine, Heine Holger, Ulmer Artur J, Rietschel Ernst Th, Zähringer Ulrich
Abstract excerpt
One major component of the Salmonella enterica sv. Minnesota Re deep rough mutant (strain R595) lipopolysaccharide is hepta-acyl lipid A (LA(hepta)). In a recent publication [Tanamoto K-I, Azumi S. Salmonella-type heptaacylated lipid A is inactive and acts as an antagonist of lipopolysaccharide action on human line cells. J Immunol 2000; 164: 3149-3156] the corresponding synthetic hepta-acyl lipid A (compound...
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