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Recognition of LPS by TLR4: Potential for Anti-Inflammatory Therapies

23 Jul 2014

Abstract excerpt

LPS molecules of marine bacteria show structures distinct from terrestrial bacteria, due to the different environment that marine bacteria live in. Because of these different structures, lipid A molecules from marine bacteria are most often poor stimulators of the Toll-like receptor 4 (TLR4) pathway. Due to their low stimulatory potential, these lipid A molecules are suggested to be applicable as antagonists of...

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PMID: 25056632
DOI: 10.3390/md12074260

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