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Article

ATP-binding cassette transporter A1 locus is not a major determinant of HDL-C levels in a population at high risk for coronary heart disease.

Atherosclerosis - 1 Feb 2003

Kakko Sakari, Kelloniemi Jani, von Rohr Peter, Hoeschele Ina, Tamminen Minna, Brousseau Margaret E, Kesäniemi Y Antero, Savolainen Markku J

Abstract excerpt

ATP-binding cassette transporter A1 (ABCA1) transports cellular cholesterol to lipid-poor apolipoproteins. Mutations in the ABCA1 gene are linked to rare phenotypes, familial hypoalphalipoproteinemia (FHA) and Tangier disease (TD), characterized by markedly decreased plasma high-density lipoprotein cholesterol (HDL-C) levels. The aim was to test if the ABCA1 locus is a major locus regulating HDL-C levels in the...

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Identifiers

PMID: 12535741
DOI: 10.1016/s0021-9150(02)00232-0

Genes

ABCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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