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Article

Common and rare ABCA1 variants affecting plasma HDL cholesterol.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2000

Wang J, Burnett J R, Near S, Young K, Zinman B, Hanley A J, Connelly P W, Harris S B, Hegele R A

Abstract excerpt

Mutations in ABCA1, a member of the ATP-binding cassette family, have been shown to underlie Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA), which are genetic disorders that are characterized by depressed concentrations of plasma high density lipoprotein (HDL) cholesterol. An important question is whether common variants within the coding sequence of ABCA1 can affect plasma HDL cholesterol in...

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Source

Identifiers

PMID: 10938021
DOI: 10.1161/01.atv.20.8.1983

Genes

ABCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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