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Article

ABCA1(Alabama): a novel variant associated with HDL deficiency and premature coronary artery disease.

Atherosclerosis - 1 Oct 2002

Hong Seung Ho, Rhyne Jeffrey, Zeller Karen, Miller Michael

Abstract excerpt

The ATP-binding cassette transporter, ABCA1, is a member of the ABC superfamily of proteins involved in the active transport of substrates across cellular membranes. Recent studies have implicated mutations in ABCA1 as the cause of Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA). To evaluate the molecular basis of low high density lipoprotein (HDL) in a family with premature coronary artery...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12204794
DOI: 10.1016/s0021-9150(02)00106-5

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ABCA1(Alabama): a novel variant associated with HDL deficiency and premature coronary artery disease.PMID 12204794Read ↗

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ATP-binding cassette transporter A1 locus is not a major determinant of HDL-C levels in a population at high risk for coronary heart disease.Semantic proximity Read ↗

Common variants in the gene encoding ATP-binding cassette transporter 1 in men with low HDL cholesterol levels and coronary heart disease.Semantic proximity Read ↗

ATP binding cassette transporter A1--key roles in cellular lipid transport and atherosclerosis.Semantic proximity Read ↗

Novel mutations of ABCA1 transporter in patients with Tangier disease and familial HDL deficiency.Semantic proximity Read ↗

Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene.Semantic proximity Read ↗

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Novel mutations in ABCA1 gene in Japanese patients with Tangier disease and familial high density lipoprotein deficiency with coronary heart disease.Semantic proximity Read ↗

Screening for functional sequence variations and mutations in ABCA1.Semantic proximity Read ↗

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