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Article

Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia.

American journal of physiology. Lung cellular and molecular physiology - 1 Feb 2003

Sood Harpreet S, Hunt Matthew J, Tyagi Suresh C

Abstract excerpt

To test the hypothesis that endothelial dysfunction in hyperhomocysteinemia was due to increased levels of nitrotyrosine and matrix metalloproteinase (MMP) activity in response to antagonism of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), cystathionine beta-synthase (CBS) -/+ mice were bred, tail tissue was analyzed for genotype by PCR, and tail vein blood was analyzed for homocysteine (Hcy) by...

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Source

Identifiers

PMID: 12533311
DOI: 10.1152/ajplung.00183.2002

Genes

CBS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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