Article
Definitive separation of graft-versus-leukemia- and graft-versus-host-specific CD4 <sup>+</sup> T cells by virtue of their receptor β loci sequences
16 Jan 2003
Abstract excerpt
Although graft-versus-host (GVH) disease (GVHD) is usually associated with graft versus leukemia (GVL), GVL can occur in the absence of clinical GVHD. There is evidence to suggest that GVL and GVH are mediated by different clones of T cells. The objective of this study was to identify the two types of T cells based on their receptor sequences. To this end we used irradiated nonleukemic cells from recipients as...
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