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Article

Tissue-restricted T cell alloresponses across HLA barriers: selection and identification of leukemia-restricted CTL in HLA-mismatched stimulator-responder pairs.

Bone marrow transplantation - 1 Aug 2003

Fujiwara H, Sconocchia G, Melenhorst J, Eniafe R, Nakamura R, Hensel N, Barrett A J

Abstract excerpt

Exploiting the graft-versus-leukemia (GVL) effect in mismatched transplants requires its separation from graft-versus-host disease (GVHD). We generated leukemia-specific cytotoxic T lymphocytes (CTL) in three haplotype-mismatched, two class I-mismatched and two single HLA-A locus-matched stimulator-responder pairs. Six patients with chronic myelogenous leukemia and one patient with acute myeloid leukemia...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Receptors, Interleukin-2

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Source

Identifiers

PMID: 12900773
DOI: 10.1038/sj.bmt.1704142

Genes

CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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