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Article

Regulation of fat storage and reproduction by Krüppel-like transcription factor KLF3 and fat-associated genes in Caenorhabditis elegans.

Journal of molecular biology - 19 Aug 2011

Zhang Jun, Bakheet Razan, Parhar Ranjit S, Huang Cheng-Han, Hussain M Mahmood, Pan Xiaoyue, Siddiqui Shahid S, Hashmi Sarwar

Abstract excerpt

Coordinated regulation of fat storage and utilization is essential for energy homeostasis, and its disruption is associated with metabolic syndrome and atherosclerosis in humans. Across species, Krüppel-like transcription factors (KLFs) have been identified as key components of adipogenesis. In humans, KLF14 acts as a master transregulator of adipose gene expression in type 2 diabetes and cis-acting expression...

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Source

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Identifiers

PMID: 21704635
DOI: 10.1016/j.jmb.2011.06.011
PMCID: PMC4371853

Genes

KLF3
KLF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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