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Article

Fat Metabolism Regulates Satiety Behavior in C. elegans.

Scientific reports - 21 Apr 2016

Hyun Moonjung, Davis Kristen, Lee Inhwan, Kim Jeongho, Dumur Catherine, You Young-Jai

Abstract excerpt

Animals change feeding behavior depending on their metabolic status; starved animals are eager to eat and satiated animals stop eating. C. elegans exhibits satiety quiescence under certain conditions that mimics many aspects of post-prandial sleep in mammals. Here we show that this feeding behavior depends on fat metabolism mediated by the SREBP-SCD pathway, an acetyl-CoA carboxylase (ACC) and certain nuclear...

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Identifiers

PMID: 27097601
DOI: 10.1038/srep24841
PMCID: PMC4838937

Genes

SCD

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