Article
Coupled translation of the respiratory syncytial virus M2 open reading frames requires upstream sequences.
The Journal of biological chemistry - 10 Jun 2005
Gould Phillip S, Easton Andrew J
Abstract excerpt
We have investigated the mechanism of the translation of the second open reading frame (ORF) of the respiratory syncytial virus M2 transcript that uses a novel coupled translation process requiring prior translation of the upstream ORF. The second M2-2 ORF sequences play no role in the coupling process and can be replaced with other gene sequences. Surprisingly, the overlap region of the two ORFs alone was not...
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