Article
Composition of the sequence downstream of the dengue virus 5' cyclization sequence (dCS) affects viral RNA replication.
Virology - 20 Jan 2012
Friebe Peter, Peña José, Pohl Marie O F, Harris Eva
Abstract excerpt
RNA replication of dengue virus (DENV) requires an RNA-RNA mediated circularization of the viral genome, which includes at least three sets of complementary RNA sequences on both ends of the genome. The 5' and the 3' untranslated regions form several additional RNA elements that are involved in regulation of translation and required for RNA replication. Communication between the genomic termini results in a...
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