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Human Papillomavirus Type 16 E2 Protein Has No Effect on Transcription from Episomal Viral DNA

13 Jan 2003

Abstract excerpt

The human papillomavirus (HPV) E2 protein plays an important role in viral DNA replication. Many studies with high-risk HPVs have demonstrated that the E2 protein can also repress transcription of the E6 and E7 oncogenes. This conclusion, based on experiments carried out with cervical cancer cells bearing integrated HPV genomes, is currently assumed to be applicable to the normal HPV life cycle, in which the...

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PMID: 12525636
DOI: 10.1128/jvi.77.3.2021-2028.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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