Article
Cell-type-specific separate regulation of the E6 and E7 promoters of human papillomavirus type 6a by the viral transcription factor E2.
Journal of virology - 1 Sept 1997
Rapp B, Pawellek A, Kraetzer F, Schaefer M, May C, Purdie K, Grassmann K, Iftner T
Abstract excerpt
Gene expression of human papillomaviruses (HPV) is tightly controlled by cellular factors and by the virally encoded E2 protein through binding to distinct sites within the regulatory noncoding region. While for the high-risk genital papillomaviruses a single promoter drives the expression of all early genes, a second promoter present in the E6 open reading frame of the low-risk HPV type 6 (HPV6) would allow an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
