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Article

SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant.

Genetics - 1 Dec 2002

Fischbeck Julie A, Kraemer Susan M, Stargell Laurie A

Abstract excerpt

Little is known about TATA-binding protein (TBP) functions after recruitment to the TATA element, although several TBP mutants display postrecruitment defects. Here we describe a genetic screen for suppressors of a postrecruitment-defective TBP allele. Suppression was achieved by a single point mutation in a previously uncharacterized Saccharomyces cerevisiae gene, SPN1 (suppresses postrecruitment functions gene...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12524336
DOI: 10.1093/genetics/162.4.1605
PMCID: PMC1462358

Genes

TBP
CYC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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