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Article

Cyclin B1 expression and p53 status in squamous cell carcinomas of the head and neck.

Anticancer research - 1 Oct 2011

Hoffmann Thomas K, Trellakis Sokratis, Okulicz Kornelia, Schuler Patrick, Greve Jens, Arnolds Judith, Bergmann Christoph, Bas Murat, Lang Stephan, Lehnerdt Götz, Brandau Sven, Mattheis Stefan, Scheckenbach Kathrin, Finn Oliviera J, Whiteside Theresa L, Sonkoly Enikö

Abstract excerpt

BACKGROUND: The cyclin B1/CDC2 complex governs entry into mitosis by regulating the G(2)/M checkpoint, and it can be repressed by the tumor suppressor p53. We aimed to determine cyclin B1 expression in squamous cell carcinomas of the head and neck (SCCHN) and correlate it with p53 status and clinicopathological parameters. PATIENTS AND METHODS: Cyclin B1 and p53 protein expression was analyzed by...

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Identifiers

PMID: 21965721
PMCID: PMC3721303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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