Article
[ATM and Cancer].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2002
Tang Yi
Abstract excerpt
The mutation of AT gene (ATM) leads to the AT disease (ataxia telangiectasis), the cancer incidence of AT patients and its carriers are significantly higher than the normal persons. And they are easy to have lymphoid tumors, including the lymphoma and leukemia et al. These indicate the ATM play a important role in the cancers pathogenesis mechanism. The ATM gene locate in the human chromosome 11q22-23, and the...
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