Article
Detection of pleiotropic effects of quantitative trait loci in outbred populations using regression analysis.
Journal of dairy science - 1 Dec 2002
Schrooten C, Bovenhuis H
Abstract excerpt
In this paper a method is presented to determine pleiotropic quantitative trait loci (QTL) or closely linked QTL in an outbred population. The method is based on results from single-trait analyses for different traits and is derived for a granddaughter design. The covariance between estimated contrasts of grandsires obtained in single-trait regression analysis is computed. When there is no pleiotropic QTL, the...
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