Article
Quantitative trait locus analysis in crosses between outbred lines with dominance and inbreeding.
Genetics - 1 Sept 2001
Pérez-Enciso M, Fernando R L, Bidanel J P, Le Roy P
Abstract excerpt
We provide a theoretical framework for quantitative trait locus (QTL) analysis of a crossed population where parental lines may be outbred and dominance as well as inbreeding are allowed for. It can be applied to any pedigree. A biallelic QTL is assumed, and the QTL allele frequencies can be different in each breed. The genetic covariance between any two individuals is expressed as a nonlinear function of the...
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