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Article

Targeted disruption of the alpha-amylase gene in the hyperthermophilic archaeon Sulfolobus solfataricus.

Journal of bacteriology - 1 Jan 2003

Worthington Penny, Hoang Viet, Perez-Pomares Francisco, Blum Paul

Abstract excerpt

Sulfolobus solfataricus secretes an acid-resistant alpha-amylase (amyA) during growth on starch as the sole carbon and energy source. Synthesis of this activity is subject to catabolite repression. To better understand alpha-amylase function and regulation, the structural gene was identified and disrupted and the resulting mutant was characterized. Internal alpha-amylase peptide sequences obtained by tandem mass...

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Identifiers

PMID: 12511494
DOI: 10.1128/JB.185.2.482-488.2003
PMCID: PMC145338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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