Article
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology.
Cell research - 1 Jan 2008
Shuck Sarah C, Short Emily A, Turchi John J
Abstract excerpt
Repair of bulky DNA adducts by the nucleotide excision repair (NER) pathway is one of the more versatile DNA repair pathways for the removal of DNA lesions. There are two subsets of the NER pathway, global genomic-NER (GG-NER) and transcription-coupled NER (TC-NER), which differ only in the step involving recognition of the DNA lesion. Following recognition of the damage, the sub-pathways then converge for the...
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