Article
H pylori (CagA) and Epstein-Barr virus infection in gastric carcinomas: correlation with p53 mutation and c-Myc, Bcl-2 and Bax expression.
World journal of gastroenterology - 14 Feb 2008
Lima Valeska Portela, de Lima Marcos Antonio Pereira, André Angela Rosa, Ferreira Márcia Valéria Pitombeira, Barros Marcos Aurélio Pessoa, Rabenhorst Sílvia Helena Barem
Abstract excerpt
AIM: To investigate the interrelationship between H pylori and Epstein-Barr virus (EBV) infection in the gastric carcinogenesis having in focus the p53 mutation and the c-Myc, Bcl-2 and Bax expression. METHODS: seventy-one gastric carcinoma tissues were assessed by polymerase chain reaction (PCR) for H pylori and in situ hybridization for EBV. c-Myc, Bcl-2 and Bax expression were detected by immunohistochemistry...
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