Article
Expression of Sox9 in granulosa cells lacking the estrogen receptors, ERalpha and ERbeta.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2003
Dupont Sonia, Dennefeld Christine, Krust Andrée, Chambon Pierre, Mark Manuel
Abstract excerpt
Ovaries from adult mice lacking both estrogen receptors ERalpha and ERbeta (ERalphabetaKO mice) contain abnormal cells sharing morphologic features with Sertoli cells, which are located mainly in the interstitial compartment. We show here that these cells express the Sertoli cell markers TIF1beta, TIF2, and Sox9. In ERalphabetaKO ovaries, Sox9 is expressed by granulosa cells before the morphologic appearance of...
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