Article
Follicular cells acquire sertoli cell characteristics after oocyte loss.
Endocrinology - 1 Jul 2005
Guigon Céline J, Coudouel Noëlline, Mazaud-Guittot Séverine, Forest Maguelone G, Magre Solange
Abstract excerpt
Although it has been suggested that in mammals the loss of female germ cells may induce the masculinization of the ovarian compartment, there has been as yet no conclusive demonstration. To directly address that question, the present study has been designed to determine the fate of follicular cells after oocyte loss. Using gamma-irradiation to selectively deplete oocytes in nongrowing follicles in female rats, we...
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