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Article

The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation

1 Dec 2002

Abstract excerpt

Telomerase, the ribonucleoprotein complex involved in telomere maintenance, is composed of two main components: hTERT and hTERC. hTERT seems to be the rate-limiting factor for telomerase activity, although hTERC expression was also shown to correlate to a certain extent with telomerase reactivation. To determine whether the absence of hTERC expression could be the consequence of DNA methylation, we quantified...

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Share to Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12507925
DOI: 10.1093/carcin/23.12.2025

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